Hence I look at individual differences, though of small interest to the systematist, as of the highest importance for us, as being the first step towards such slight varieties as are barely thought worth recording in works on natural history.

And I look at varieties which are in any degree more distinct and permanent, as steps toward more strongly marked and permanent varieties; and at the latter, as leading to sub-species, and then to species.

The passage from one stage of difference to another may, in many cases, be the simple result of the nature of the organism and of the different physical conditions to which it has long been exposed; but with respect to the more important and adaptive characters, the passage from one stage of difference to another may be safely attributed to the cumulative action of natural selection, hereafter to be explained, and to the effects of the increased use or disuse of parts.